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AgNOR quantitative image analysis in corneal and conjunctival limbal epithelial benign and malignant lesions in the diagnosis of


1997-12-15 Revised) down 1: Male,moncler zürich, 1.5 years old. Limitations found in the right department head Xu painless mass 5 a month. Subcutaneous tumor in the right top of the head, irregular-shaped,abercrombie and fitch, about 4cm × 3cm × 0.5cm, ill-defined, relatively fixed base,moncler 2012, surrounded by no swelling. CT showed no abnormal laboratory head at the top of the right subcutaneous tumor, consider lipoma. Line of tumor resection. Example 2: Female,Moncler Outlet, ¨ years old. 1 year left knee tumor cases and people's homes. Examination see the left knee joint swelling, skin temperature slightly higher, can reach a 4cm × 3cm × 2cm tumor, swelling brazing can be activities, tenderness,abercrombie deutschland, joint activities are not limited, the femoral artery Pollex normal, no paresthesia. MR1 distal left thigh shows soft tissue mass with old hemorrhage. Suddenly cut off the line tumor surgery. Down 3: Male, 9 years old Ministry of tumor left floating over six years, increasing large. Swollen left floating in the Ministry of brazing, soft, irregular-shaped, about 4cm × 3cra) <3cm, state of confusion, the more fixed base, no tenderness, no abnormal skin surface. Clinical diagnosis of lipoma, surgical excision. Irregular buildings compared with the pathological tissue mass inspection children were 3.5cm × 3cm × 0.8cm, 4.5cm × 3.5cm × 3cm and 4cm × 3cm × 3cm. Generally seen similar, no capsule, cut gray, gray-yellow phase Q, stroma. Microscope, the tumor was composed of 3 components staggered form (Figure 1): (1) by fibroblasts and collagen fibers to form fiber-like rules of the beam spacing. Edge thin, like a small, chest pulp chatter acid} (2) sparse orange mucus-like matrix, which asked to do in a relatively immature ring-shaped or stellate-shaped small cells (Figure 2) I (3) into the hot fat tissue was island-like distribution. Immunohistochemistry showed positive vimentin Mi grab 'ten other spindle cell actln positive. Pathological diagnosis: infants fibrous hamartoma. Discussion of the disease Reye in 1956 by the first reported at the time known as the baby subcutaneous fibrous tumors. Detailed characteristics of the disease later Enzinger, and changed its name to the baby fibrous hamartoma (fibroushamartomaofinfancy, FH1). Occur in infants less than 2 years, the average age of l0 October, also found in small scattered ill children. Male to female ratio 2l. About 1 / 5 patients with lesions at birth, but the author units; Beijing Medical Science 100,044 people hide scaphoid non familial. The most common site for the armpit, shoulder, upper arm, followed by the thigh, degree of thigh, the scrotum and the head and face. Almost all cases were solitary nodules, ill-defined, growing more rapidly. Exploration in the dermis or subcutaneous layer, sometimes fixed on the basement membrane marrow or muscle surface, not involving the muscle layer probe. The Department of benign tumors, complete removal of cured and rarely relapse. Gross examination FHI ill-defined, no capsule. Its texture, color due to the proportion of fat varies. Tumor size is usually 3 ~ 5cm, up l5cm. Histology showed hamartoma of three components: spindle-shaped fibroblasts or myofibroblasts; in the mucus matrix naive to ask a small round or stellate-shaped leaf cells' with varying amounts of mature adipose tissue. Immunohistochemistry showed that the three components showed vimentin expression, into the hot fat, S-100 protein-positive, part of the spindle cells and naive cells were actln asked leaf expression. Electron microscopy confirmed the spindle cells to fibroblasts or myofibroblasts' nuts liquid matrix in small round or stellate-shaped cells, leaf cells need to ask for the naive identification of the disease are: (D Baby fibromatosis: locally invasive and difficult to complete resection, recur. FHI occurred over parts of the probe, located in the striated asked, mainly by the different microscopic tumor differentiation stages of fibroblast cells and young cells, striated asked Mi grab filled in (2) fibrolipoma: When FHI fat than the side more, often misdiagnosed as fibrolipoma but fibrolipoma clear boundary can be lobulated, fluid-like matrix and the lack of nuts naive asked leaf cells (3) Calcifying aponeurotic fibroma: age of onset more FHI large, mainly seen in children and adolescents; lesions to the hands, feet common. fibroblasts were taught microscopic nodular aggregation, the question may have islands of cartilage and calcification (4) myofibroblasts fibromatosis : for single or multiple lesions, some sick with familial, tumor state more clearly, and often occur in internal organs, a single microscopic cell morphology, cytoplasmic chatter acid. the United States lay term hamartoma, infant diagnosis, identification of words in the book field circle R730.261 (1997-11-17 Received) (see inset photo on page 47)
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