Abstract Objective Doppler tissue imaging evaluation of high blood sugar in diabetic patients with left ventricular systolic and diastolic function and structure. Method 17 cases of diabetes before admission, poor blood sugar control in patients immediately after admission line two-dimensional echocardiography (2DE) and pulsed Doppler tissue imaging (DTI) checks, blood glucose control and stability, review of the indicators prior to discharge. Results high blood sugar and blood glucose control before and after the fall, echocardiography: ejection time (ejectti), left ventricular posterior wall thickness (lvpw), through the mitral isovolumic contraction time (maivct) , E-wave deceleration time (edt2), a late diastolic peak velocity loop (a loop am) changed significantly, but did not reach statistical standards, 0.05 P P <0.05). Conclusion of hyperglycemia on the myocardium is an early, independent, short-term changes in blood sugar can cause cardiac dysfunction, but simple control of blood glucose no significant changes in the short term echocardiography. Key words Doppler tissue imaging of left ventricular function high blood sugar ; [Abstract] Objective Doppler tissue imaging (DTI) was used in diabetic patients to evaluate the influence of hyperglycemia to the structure,
sac hermes birkin, systole and diastole function of left ventricular. Methods 2DE and DTI were performed in 17 diabetic patients with poor glycemic control.2DE and DTI were performed right after their admission to the hospital and re-evaluated when glycemic control was improved. Results Some parameters of left ventricular changed clearly but not significantly between the first and second examination, such as ejection time, thickness of posterior wall, isovlumetric contraction time,
franklin marshall femme, E wave deceleration time and A cyclic late relaxation peak velocity (0.05 P P <0.05). Conclusion Hyperglycemia has an early and independent influence to myocardia.The glycemic control in short term might lead to alterations of myocardial function, but the parameters of DTI would not change significantly. [Key words] Doppler tissue imaging hyperglycemia left ventricular function independent diabetes in hypertension, coronary heart disease affect the structure and function, regardless of type 1 and type 2 diabetes, in the absence of coronary artery disease, valvular disease and high blood pressure cases can lead to cardiac dysfunction [1]. The purpose of this study by Doppler tissue imaging of mitral annular velocity of quantitative analysis, evaluation of patients with diabetes in high glucose and blood glucose control shortly after a good left ventricular systolic and diastolic function and structural changes in order to Indirect evidence independent of the capillary blood sugar, large vessel disease and coronary heart disease, high blood pressure leading to cardiac dysfunction. 1 Materials and Methods 1.1 General Information April 2, 2004 in our hospital inpatient endocrinology diabetes, screening associated with acute infections, heart valve disease, lipid-lowering drugs after admission application or antihypertensive drugs change, or combined with ACEI or ARB class, poor blood sugar control prior to admission, fasting blood glucose> 7.0mmol / L, and (or) 2h postprandial glucose> 10.0mmol / L, and (or) glycated hemoglobin> 8.0% immediately after admission line two-dimensional echocardiography (2DE) and pulsed Doppler tissue imaging (DTI) checks,
abercrombie marseille, blood glucose control is stable prior to discharge review of the indicators, select the 41 indicators used for analysis. Eligible patients were 17 cases, 10 males, 7 females, had no history of coronary heart disease, 2 patients with hypertension, mean age (48.3 ± 8.9) years, Table 1. Table 1 Selected patient Basic 1.2 blood glucose monitoring method applied Johnson & Johnson glucose meter to calculate the time of admission and fasting blood sugar stable and 2h postprandial blood glucose average. Lipids, fructosamine and other biochemical applications Hitachi 7200 automatic biochemical analyzer determination of glycated hemoglobin by high performance liquid method. Cardiac Doppler ultrasound examination of the instruments for the U.S. company GE's VIVID 7 color Doppler imaging device, the probe frequency of 1.7 ~ 3.4MHz, probing depth of 15 ~ 18cm, scan angle of 90 ~ 120 °, frame rate> 60 / s. Check the connection synchronization ECG monitoring, images are quiet breathing in subjects with the state to obtain. Acquired images were stored on MO or hard drive for later offline processing and analysis. 1.3 parameters measured M-mode echocardiography: left ventricular end systolic diameter (LVIDs), left ventricular end-diastolic diameter (LVIDd), diastolic interventricular septum thickness (IVSD) and left ventricular posterior wall thickness (LVPWD), fractional shortening (FS%), stroke volume (SV) and left ventricular mass (LVmass), left atrial diameter ( LA). Simpson through improved method to calculate left ventricular ejection fraction (LVEF). The mitral inflow: speed parameters: early diastolic peak filling velocity (E), diastolic peak filling velocity (A), E / A. Velocity time integral: early diastolic filling time velocity integral (EVTI), diastolic filling time velocity integral (AVTI), EVTI / AVTI. Time parameters: E peak deceleration time (EDT), A peak time (Ta). Aortic flow spectrum: intra-aortic peak flow velocity (AOV), aortic ejection time (b), dp / dt (+) and dp / dt (-). Right upper pulmonary venous flow: systolic pulmonary vein peak velocity (S wave), early diastolic pulmonary vein peak velocity (D wave), atrial systolic pulmonary venous negative wave peak velocity (A wave), A wave duration (Tpva), by the formula calculate MPI: MPI = (ab) / b. Tissue velocity imaging: speed parameters: peak systolic velocity (Sm), peak early diastolic velocity (Em), diastolic peak velocity (Am),
abercrombie femmes, Em / Am. Time parameters: Em deceleration time (EDT '), Am duration (Ta'), Sm duration (b '), isovolumic contraction time (IVCT), isovolumic relaxation time (IVRT). 1.4 statistical methods to measure data are mean ± standard deviation ( x ± s ) that the use of paired t test, data processing using SPSS 11.5 statistical analysis software package, P <0.05 for the difference was significant. 2 results differences in blood glucose down There was a significant ( P <0.01), including fasting blood glucose, 2h postprandial glucose, glycated hemoglobin, glycated serum protein, total cholesterol, LDL decreased significantly, Table 2. Echocardiography: ejection time (ejectti), left ventricular posterior wall thickness (lvpw), through the mitral isovolumic contraction time (maivct), E peak deceleration time (edt2), a ring diastolic peak velocity (a ring am) change significantly, but did not reach statistical standards, 0.05 P <0.2, A wave peak velocity (Da) and Doppler (isovolumic contraction time - isovolumic relaxation time) / ejection time ( doppmpi) to change the difference was significant ( P <0.05), Table 3. Table 2 Clinical data before and after treatment were Note: ▲ P
Doppler tissue imaging assessment of hyperglycemia on left ventricular function
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