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1 Department of Biostatistical Science, Dana-Farber Cancer Institute, 44 Binney St, Boston, MA 02115, USA

2 Channing Laboratory, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA

3 Department of Statistics, University of Wisconsin-Madison, 1210 W Dayton St, Madison, WI 53706,Windows 7 Home Premium 64, USA

4 Division of Biostatistics, University of California, Berkeley, 140 Warren Hall, Berkeley, CA 94720-7360, USA

5 Seminar for Statistics LEO C16, ETH Zentrum, Zürich CH-8092, Switzerl

6 Department of Statistics, Harvard University, 1 Oxford St, Cambridge, MA 02138, USA

7 Center for Biological Sequence Analysis,Microsoft Office Standard 2007 Key, Technical University of Denmark, Building 208, Lyngby 2800, Denmark

8 Department of Biomathematical Sciences, Mount Sinai School of Medicine, 1 Gustave Levy Place, Box 1023, New York, NY 10029, USA

9 Institut für Statistik und Wahrscheinlichkeitstheorie, TU Wien, Wiedner Hauptstrasse 8-10/1071, Wien 1040, Austria

10 Institut für Medizininformatik, Biometrie und Epidemiologie, Friedrich-Alexander-Universität Erlangen-Nürnberg, Waldstraße6, D-91054 Erlangen, Germany

11 Division of Molecular Genome Analysis,Windows 7 Home Basic Sale, DKFZ (German Cancer Research Center),Office Standard 2007, 69120 Heidelberg, Germany

12 Department of Economics, University of Milan, 23 Via Mercalli, I-20123 Milan, Italy

13 Department of Biostatistics, Johns Hopkins University, 615 N Wolfe St E3035, Baltimore, MD 21205, USA

14 Department of Medical Education and Biomedical Informatics, University of Washington, Box 357240, 1959 NE Pacific, Seattle, WA 98195, USA

15 Statistisches Labor, Institut für Angewandte Mathematik, Im Neuenheimer Feld 294, D 69120, Heidelberg, Germany

16 Department of Molecular Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, TPC-28, La Jolla, CA 92037, USA

17 Division of Genetics and Bioinformatics,Office 2007 Enterprise jhgjhg, The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Victoria 3050, Australia

18 Department of Statistics and Actuarial Science, University of Iowa, 241 Schaeffer Hall, Iowa City, IA 52242, USA

19 Center for Bioinformatics and Molecular Biostatistics,Buy Office 2007 Key, Univerisity of California, San Francisco, 500 Parnassus Ave, San Francisco 94143-0560, USA