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150088 2011 年 02 月 14 日 16:43 Reading (loading. ..) Comments (0) Category: Technical Information
Collagen is a protein, its English name Collagen is a white, opaque, non-branched fiber protein, which is mainly found in animal skin, bone, cartilage, teeth, tendons, ligaments and blood vessels, is a very important structural protein of connective tissue, plays a supporting organs, protect the body's functions. Collagen is the most abundant protein in mammals, accounting for 25% of the total amount of protein -30%, equivalent to 6% of body weight.
Collagen is the extracellular matrix (EMC) of the main compound, with the biochemistry, molecular biochemistry and cellular biochemistry progress, people's understanding of the gradual increase of collagen , is now certainly is not a collagen protein name, and immunoglobulin but, like the rich diversity and tissue distribution specificity, with the tissues and organs function on the functional protein. According to their distribution and function in the body, and can be divided into the collagen collagen, basement membrane collagen and extracellular collagen week.
Collagen is a protein family, is now found in 18 or 19 members, from the skin and bone collagen Ⅰ isolated from cartilage isolated Ⅱ collagen, isolated from the embryonic skin of type Ⅲ collagen, isolated from the cells out of the basement membrane collagen type Ⅳ, which are through the primary structure of the protein level analysis, while the other is the nucleic acid level by collagen domain similarity analysis found.
collagen molecular weight 300,000 Dalton, which is a combination of three peptides of the triple helix structure,
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collagen protein structure and function of the diversity and complexity,
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protein is the most important constituents of living organisms, including coverage of human skin,
nike air force one, hair is made up of protein. In addition, the protein is almost dominated the lives of all biological activities, such as: cell division, metabolism, transmission of information, as well as resistance to disease are dependent on the protein to complete.
Therefore, in cosmetics, to the protein as an active substance is natural. CTFA Cosmetic Ingredients Handbook U.S. employment of natural substances and the Collagen as a very effective class of cosmetic raw materials,
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as collagen and collagen hydrolysates with a similar structure of human skin, good compatibility, there are ionic bonds, hydrogen bonds and other interactions; by preparing the material, can spread deep into the skin, human skin has a good nutrition role; same time, because its molecule contains a large number of hydroxyl groups, so it has very good moisturizing effect; the molecule amino and carboxyl groups but also the surface give it a certain activity, which makes it compatible with other materials is very good, and non-irritating to the skin; with age, the synthesis of fibroblasts reduced capacity, if the lack of collagen in the skin, collagen fibers associated curing occurs , mucopolysaccharide between the cells decreased, the skin will lose the soft, elastic and shiny, with aging, and leather fiber rupture,
nike air force one low, fat atrophy, sweat glands and sebaceous glands reduced to skin pigmentation, wrinkles and a series of aging. Collagen as an effective cosmetic ingredients, to moisturize the skin, giving it the smooth feel of hair has a very good conditioning effect. In the United States, Germany, Japan and other countries, adding there are many high-end cosmetics, collagen, or collagen injections in the human face to keep skin youthful and reducing wrinkles.
in foreign countries, of collagen in the role of beauty has conducted in-depth study. Tests to prove: 0.01% pure collagen solution had a good effect against a variety of radiation, and can form a good water level, can supply all the water needed for the skin. Collagen used in cosmetic efficacy sum up the following points:
(1) may be given nutritional
layers of the skin containing collagen nutrients necessary to supplement the 17 amino acids beneficial to human body, so that activity in the collagen of the skin to enhance and maintain water and fiber structure of the stratum corneum integrity and improve the living environment and promote skin cell skin tissue metabolism, increase circulation, hydrate the skin, anti-aging, beauty, eliminate wrinkles, hair care effect.
(2) repair of
collagen and the surrounding tissue affinity for good, so the repair tissue effect.
(3) moisture
the collagen molecule contains a large number of hydrophilic groups, so good moisturizing effect, can achieve the purpose of keeping the skin moist.
(4)
compatibility and stability of collagen,
nike air force one high, can regulate the pH, stable foam, emulsion colloid effect. Meanwhile, as a functional ingredient in cosmetics can reduce the various surface active agents, acids, alkalis and other irritating substances on the skin, hair damage.
(5) affinity
collagen on the surface of the skin and hair have a greater affinity for protein molecules, collagen mainly through physical adsorption combined with skin and hair, the ability to rinse treatment. Affinity with increasing molecular weight increased. Small molecular weight molecules can penetrate the skin and hair, skin, and sometimes through the cortex layer, to achieve nutritional skin. Large molecular weight molecules, each molecule binding sites are more enhanced binding affinity increases.
moderate collagen protein product performance, features and more, safe, in line with the trend of modern cosmetics, is the important raw material for high-end cosmetics. International sales of cosmetics raw materials used in nearly 50 species of proteins, only the N-acylation of hydrolyzed collagen protein condensates, sarcosine, serine, and hyaluronic acid and a few rough several products for sale.
Currently, Universal Mu, who has been established from animal collagen, the extraction level in line with national food hygiene methods collagen products, is developing a series of collagen protein cosmetics.
With the development of biochemistry and molecular biology, biological materials are increasingly used in cosmetics. Collagen is bound as a functional cosmetic raw materials of biological material to become a key member of the series for the young man to maintain an increasing role to play.
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